Department of Biology · Baylor University
Design principles of microbial life
We combine multi-omics with mechanistic, data-constrained models to understand how microbes and microbial communities work, and how they evolve.
Welcome
The BioJazz Lab, led by Dr. Song Feng, studies the design principles behind microbial physiology and microbial communities in the context of evolution and ecology.
We integrate multi-omics measurements, such as proteomics and metabolomics, with computational modeling. A central goal is to build mechanistic yet data-constrained virtual cell models that can guide the design of microbial communities. We also use AI and automation to build models, tools, and software for systems biology.
The lab shares its name with BioJazz, our software for the in silico evolution of cellular networks.
Research areas
Virtual cells for microbial communities
Mechanistic, data-constrained models of microbial physiology to understand and design microbial communities.
Phage–host metabolic interactions
How bacteriophages rewire the metabolism of their hosts, studied with genome-scale models.
Protein modifications, structure & regulation
Linking post-translational modifications to protein structure and function with proteomics, modeling, and AI.
Evolution of cellular networks
In silico evolution and analysis of signaling and regulatory networks, including our BioJazz software.
Latest news
August 1, 2026
The BioJazz Lab opens at Baylor University
Dr. Song Feng has joined the Department of Biology at Baylor University as an Assistant Professor, launching the BioJazz Lab. We are recruiting graduate students, postdocs, and undergraduate researchers. See Join Us.
April 1, 2026
Paper on metabolic hijacking by bacteriophages published in Science Advances
Our paper “Synergy and antagonism in a genome-scale model of metabolic hijacking by bacteriophages” is now out in Science Advances. Read the paper.